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This report describes the Na2PtCl4 catalyzed C-H arylation of arene substrates with diaryliodonium salts. The site selectivity of these reactions is predominantly controlled by steric factors. Remarkably, Na2PtCl4-catalyzed naphthalene arylation proceeds with opposite site selectivity compared to that obtained with Na2PdCl4 as the catalyst. Preliminary mechanistic studies provide evidence for a Pt(II)/Pt(IV) catalytic cycle involving rate-limiting C-C bond-forming reductive elimination.
Wagner et al. (Tue,) studied this question.
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