Diabetes in patients with first-ever stroke was associated with more ischaemic strokes (92.1% vs 71.3%) but similar in-hospital mortality (18.2% vs 16.9%) compared to non-diabetics.
Observational (n=2,532)
Does the presence of diabetes alter stroke subtypes and in-hospital mortality in Chinese patients with first-ever stroke?
In Chinese patients with first-ever stroke, diabetes is associated with a higher frequency of ischaemic stroke and lacunar infarction but a lower frequency of cerebral haemorrhage, without increasing in-hospital mortality for ischaemic stroke.
Absolute Event Rate: 18.2% vs 16.9%
In this study, demographic characteristics, risk factors, stroke subtypes and outcome were compared in 2532 patients with and without diabetes hospitalized for first-ever stroke. Diabetes was present in 471 (18.6%) of the patients. Patients with diabetes presented more frequently with ischaemic stroke (92.1% versus 71.3%), especially lacunar infarction (41.2% versus 35.2%), compared with non-diabetics. Cerebral haemorrhage was less frequent in diabetics than non-diabetics (4.2% versus 18.1%). In-hospital mortality rates from ischaemic stroke were similar in the two groups (18.2% in diabetics and 16.9% in non-diabetics). Predictors of in-hospital mortality in diabetic patients included decreased consciousness, congestive heart failure and atrial fibrillation. In conclusion, stroke in diabetic patients was different to stroke in non-diabetic patients: in diabetics the frequency of cerebral haemorrhage was lower and the rate of lacunar infarct syndrome was higher, but in-hospital mortality from ischaemic stroke was not increased. Clinical factors evident at the onset of stroke have a major influence on in-hospital mortality and may help clinicians provide a more accurate prognosis.
Zhang et al. (Sun,) conducted a observational in first-ever stroke (n=2,532). Diabetes vs. Non-diabetics was evaluated on In-hospital mortality from ischaemic stroke. Diabetes in patients with first-ever stroke was associated with more ischaemic strokes (92.1% vs 71.3%) but similar in-hospital mortality (18.2% vs 16.9%) compared to non-diabetics.