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Coronary Heart DiseaseKeys and his colleagues39 have discussed the evidence derived from their seven-nation study identifying obesity as a risk factor for coronary heart disease. They preferred the body-mass index (BMI = W/H2) as the index of obesity. Although blood pressure was significantly correlated with adiposity, the association was low. Cross-classification suggested a significant excess of coronary heart disease in the upper quartile of men classified as obese when blood pressure was ignored, but the effect of obesity disappeared when only normotensive men were considered. Using multivariate analysis, the authors could show no predictive value of body fatness . . .
George V. Mann (Thu,) studied this question.