Brachial-ankle pulse wave velocity could not significantly differentiate between hypertensive patients with target organ damage and those with associated clinical conditions, suggesting it may underestimate arterial stiffness in patients with prior cardiovascular events.
Cross-Sectional (n=296)
No
Does brachial-ankle pulse wave velocity accurately evaluate cardiovascular complications in hypertensive patients compared to carotid-femoral pulse wave velocity?
Brachial-ankle pulse wave velocity may underestimate arterial stiffness in hypertensive patients with a history of cardiovascular events compared to carotid-femoral pulse wave velocity.
The goal of this study was to clarify the clinical usefulness and limitations of brachial-ankle pulse wave velocity (PWV) to evaluate hypertensive complications, in comparison with carotid-femoral PWV. Patients with essential hypertension (n=296, male/female=161/135; age=61.1+/-0.7 years) were enrolled. We measured brachial-ankle PWV, femoral-ankle PWV and carotid-femoral PWV simultaneously, and evaluated target organ damage and associated clinical conditions (cerebrovascular and cardiovascular disease) using the World Health Organization classification modified in 1999. Carotid-femoral PWV (p<0.0001; r=0.521) and brachial-ankle PWV (p<0.0001; r=0.478) but not femoral-ankle PWV were significantly correlated with age. Carotid-femoral PWV was significantly higher in patients with associated clinical conditions compared with that in patients with target organ damage (p<0.05) and those with no complications (p<0.0001). Brachial-ankle PWV was significantly higher in patients with associated clinical conditions (p<0.05) and target organ damage (p<0.05) compared to those with no complications, but there was no significant difference in brachial-ankle PWV between these two groups. Moreover, femoral-ankle PWV was significantly lower in patients with associated clinical conditions compared with that in patients with target organ damage (p<0.05). These data suggest that brachial-ankle PWV could underestimate arterial stiffness in hypertensive patients with a history of cardiovascular events.
Ito et al. (Sun,) conducted a cross-sectional in Essential hypertension (n=296). Brachial-ankle pulse wave velocity (baPWV) vs. Carotid-femoral pulse wave velocity (cfPWV) was evaluated on Difference in pulse wave velocity between patients with associated clinical conditions and target organ damage. Brachial-ankle pulse wave velocity could not significantly differentiate between hypertensive patients with target organ damage and those with associated clinical conditions, suggesting it may underestimate arterial stiffness in patients with prior cardiovascular events.
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