Sustained blood pressure control in ≥75% of visits was associated with a lower risk of the primary cardiovascular outcome compared to control in <25% of visits (HR 0.78; 95% CI 0.67-0.90).
Cohort (n=6,287)
Does consistent and sustained blood pressure control reduce cardiovascular outcomes in patients with high cardiovascular risk?
Sustained and consistent blood pressure control over time is associated with a significantly reduced risk of cardiovascular outcomes, particularly stroke, in high-risk patients.
Hazard Ratio: 0.78 (95% CI 0.67–0.9)
A retrospective further analysis of the ACTION database evaluated the relationship between cardiovascular outcomes and the "quality" of the control of blood pressure (BP). The study population (n = 6287) comprised those patients with four BP measurements during year 1 subdivided according to the proportion of visits in which BP was controlled in relation to two BP targets: ₇5% of visits with BP control than in the group with < 25% of visits with BP control. There were no significant treatment-related differences. Retrospective analyses are not definitive but these results highlight the importance of the attainment of BP control targets and the consistency of BP control during long-term follow-up.
Meredith et al. (Thu,) conducted a cohort in High cardiovascular risk (n=6,287). Sustained blood pressure control (≥75% of visits with BP controlled) vs. Poor blood pressure control (<25% of visits with BP controlled) was evaluated on Primary outcome (prespecified ACTION cardiovascular endpoint) (HR 0.78, 95% CI 0.67-0.90). Sustained blood pressure control in ≥75% of visits was associated with a lower risk of the primary cardiovascular outcome compared to control in <25% of visits (HR 0.78; 95% CI 0.67-0.90).