What does this research mean for the field?

Enrollment in a digital cardiometabolic program significantly reduces emergency room and inpatient utilization among high-risk patient subgroups with combinations of hypertension, diabetes, and obesity. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

Evaluate changes in emergency room (ER) and inpatient (IP) utilization among members in a digital cardiometabolic program compared to matched controls.

June 7, 2026

2749-LB: Reduced Emergency and Inpatient Utilization in High-Risk Subgroups Enrolled in a Digital Cardiometabolic Program Retrospective Matched Claims Analysis

Key Points

Evaluate changes in emergency room (ER) and inpatient (IP) utilization among members in a digital cardiometabolic program compared to matched controls.
Retrospective matched cohort study using employer-sponsored medical claims data.
Enrolled members were matched to non-enrolled controls, comparing pre- and post-enrollment ER and IP rates.
Wilcoxon weighted paired testing assessed within-group changes.
Among 476 members, significant reductions in ER and IP utilization were found in three high-risk subgroups versus controls.
In hypertension without diabetes, enrolled members reduced ER (−0.0799) and IP (−0.0024) (p<0.05), while controls increased ER and IP.
Results indicate reductions in ER and IP utilization across hypertension with obesity and the triad of diabetes, hypertension, and obesity.

Abstract

Introduction and Objective: Acute care utilization (emergency room ER and inpatient IP stays) remains high in cardiometabolic populations, particularly among individuals with diabetes, hypertension, and obesity. Real-world evidence is needed to identify subgroups with consistent reductions following digital health program enrollment. The objective is to evaluate changes in ER and IP utilization among members enrolled in the Dario digital health platform versus matched controls, focusing on subgroups demonstrating reductions across both outcomes. Methods: A retrospective matched cohort study was conducted using employer-sponsored medical claims data. Enrolled members in a digital cardiometabolic program were matched to non-enrolled controls. Outcomes were monthly ER and IP rates pre- vs post-index per member. Within each subgroup, we calculated pre/post enrollment changes and net differences versus controls. Wilcoxon weighted paired testing assessed within-group changes. Results: Among 476 members, three subgroups showed consistent reductions in ER and IP utilization versus controls. In hypertension without diabetes but with additional comorbidity (N=58), enrolled members reduced ER (−0.0799) and IP (−0.0024) (p0.05), while controls increased ER (+0.0088) and IP (+0.0029) (net: −0.0886 ER; −0.0053 IP). In hypertension with obesity (N=44), enrolled members reduced ER (−0.0823) and IP (−0.0036) (p0.05), with smaller changes in controls (net: −0.0305 ER; −0.0069 IP). In diabetes, hypertension, and obesity (N=83), enrolled members reduced ER (−0.0128) and IP (−0.0102) (p0.05), while controls showed minimal ER change and increased IP (+0.0090) (net: −0.0041 ER; −0.0192 IP). Conclusion: Enrollment was associated with significant reductions in care utilization, particularly among high-risk subgroups with hypertension, diabetes, and obesity, supporting the potential economic value of digital health solutions in populations at elevated risk. Disclosure Y. Fundoiano-Hershcovitz: Employee; Current; DarioHealth Corp. R. Herzfeld: Employee; Current; DarioHealth Corp. O. Manejwala: Employee; Current; DarioHealth Corp. Stock/Shareholder; Current; DarioHealth Corp.

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2749-LB: Reduced Emergency and Inpatient Utilization in High-Risk Subgroups Enrolled in a Digital Cardiometabolic Program Retrospective Matched Claims Analysis

Key Points

Abstract

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