Abstract This work presents the synthesis of two new methyl 4-6-alkyl-4-methyl-3-oxo-1H-pyrrolo3, 4-cpyridin-2 (3H) -ylbenzoates and investigates their reactions with nitrogen-containing nucleophilic reagents. The possibility of the targeted preparation of amide derivatives and benzohydrazides with high yields (54–75%) was demonstrated. The reactions proceed selectively via nucleophilic substitution and subsequent cyclization. The obtained compounds successfully participate in reactions with the chosen nucleophilic reagents and may be promising precursors for the further synthesis of biologically active substances based on the pyrrolo3, 4-cpyridine core.
Shatirova et al. (Mon,) studied this question.