Abstract Background: Prevention in clinical medicine increasingly requires approaches that address the emotional, behavioural, occupational and social determinants of health without weakening scientific standards. Chronic stress, burnout, loneliness, poor sleep, sedentary behaviour, unhealthy diet, financial strain and dysregulated digital behaviour can interact through neuroendocrine, inflammatory, behavioural and relational pathways. Creative health, arts engagement, emotional literacy and social prescribing have emerged as promising adjunctive strategies, but their clinical translation requires clear mechanisms, safety boundaries, evaluation standards and implementation logic. Objective: To synthesise selected evidence from creative health, occupational mental health, stress biology, lifestyle medicine, emotional regulation, social prescribing and implementation science, and to propose a clinically responsible Creative Health Self-Regulation Framework for preventive medicine. Methods: A quality-appraised narrative review was conducted using a structured search strategy across PubMed/MEDLINE, Google Scholar, WHO and EQUATOR Network resources, prioritising guidelines, systematic reviews, scoping reviews, landmark studies and recent 2023-2026 literature. The manuscript was organised according to the Scale for the Assessment of Narrative Review Articles (SANRA), and future trial recommendations were aligned with TIDieR, CONSORT 2025, SPIRIT and Medical Research Council guidance for complex interventions. Results: Creative and cultural engagement may support emotional expression, emotion differentiation, meaning reconstruction, social connection, behavioural activation, embodied regulation and quality of life. Evidence is heterogeneous and should not be overclaimed; however, the field is sufficiently mature to justify pragmatic feasibility studies, implementation research and carefully designed trials. The proposed framework includes eight domains: body, cognitive patterns, emotions, meaning, relationships, work, financial stressors and digital behaviour. Conclusions: Creative health can become a credible component of preventive clinical medicine when it is framed as an adjunct to care, operationalised through measurable mechanisms, protected by ethical safeguards and tested through transparent research designs. This article offers a publishable translational framework and research agenda for future clinical and occupational health studies.
Bonasa Alzuria Dr. Ignacio (Wed,) studied this question.