Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 26, 2026Archives of Orthopaedic and Trauma SurgeryOpen Access

Timing and microbiological profile influence long-term outcomes after debridement, antibiotics, and implant retention (DAIR) in acute hip periprosthetic joint infection

View Full Paper
Ask AI
Bookmark
Share

Authors

EMErnesto Muñoz-MahamudJPJuan Carlos Perdomo-LizárragaACAndrés Combalia

Discussion

Loading...

Member takes

Overview

Randomized trial evaluates treatment failure in hip infections, indicating timing and infection type matter.

Key Points

  • This study aims to analyze long-term outcomes and identify risk factors for treatment failure after DAIR in acute hip periprosthetic joint infection.
  • Retrospective analysis of 115 patients treated with DAIR for acute PJI from 1999 to 2018.
  • Evaluated predictors of treatment failure using univariate tests and Cox proportional hazards regression.
  • Mean follow-up duration of 7.1 years.
  • Treatment failure occurred in 30.4% of patients at five years.
  • Failure rates were lower for procedures within seven days of diagnosis (27.5% vs 53.8%, p = 0.05).
  • Higher failure rates noted for revision arthroplasty (48.1% vs 25%, p = 0.02) and polymicrobial infections (47.8% vs 24.5%, p = 0.04).

Cite This Study

Muñoz-Mahamud et al. (2026) studied this question.

synapsesocial.com/papers/6a3e1735030ad1a9b3090d45https://doi.org/10.1007/s00402-026-06385-2
View Full Paper
Ask AI
Bookmark
Share