Intravenous adenosine slowed the atrial rate in two patients with sinus node reentrant tachycardia and terminated the tachycardia in one.
Case Report (n=2)
Does intravenous adenosine affect atrial rate or terminate sinus node reentrant tachycardia?
Adenosine slows atrial rate and can terminate sinus node reentrant tachycardia, suggesting sinus nodal tissue involvement in the tachycardia circuit.
The effects of adenosine given during sinus node reentrant tachycardia were investigated in two patients. Both patients received intravenous bolus doses of 0.1 mg/kg and 0.15 mg/kg. Adenosine slowed the atrial rate in both patients and terminated the tachycardia in one. These effects of adenosine on sinus node reentrant tachycardia suggest that sinus nodal tissue (as opposed to perinodal atrial tissue) is involved in the tachycardia circuit and that these effects should be considered when adenosine is used as a diagnostic agent in narrow-complex tachycardia.
Griffith et al. (Sat,) conducted a case report in sinus node reentrant tachycardia (n=2). Adenosine was evaluated on atrial rate and tachycardia termination. Intravenous adenosine slowed the atrial rate in two patients with sinus node reentrant tachycardia and terminated the tachycardia in one.