Kidney transplantation in diabetic patients with end-stage renal disease is associated with better survival and quality of life compared to dialysis.
Does kidney transplantation improve survival and quality of life in diabetic patients with ESRD compared to dialysis?
Kidney transplantation offers superior survival and quality of life compared to dialysis for diabetic patients with end-stage renal disease.
It is well established that diabetic nephropathy is the most common cause or in combination with hypertensive nephropathy are the most common causes of end-stage renal disease (ESRD) in developed and developing countries. For this review, we used a variety of sources by searching through PubMed, Embase, Scopus, Current Content and Iran Medex from January 1990 up to December 2014. Manuscripts published in English and Persian languages, as full-text articles, and or as abstract were included in the study. Patient survival in diabetics on maintenance renal replacement therapy including hemodialysis (HD), peritoneal dialysis (PD) and kidney transplantation is significantly lower than that seen in nondiabetics with ESRD. The poor prognosis of diabetic patients with ESRD is partly due to presence of significant cardiovascular disease, problems with vascular access, more susceptible to infections, foot ulcer, and hemodynamic instability during HD. Although, many complications related to kidney transplantation may occur in diabetic ESRD patients, multiple studies have found that the kidney transplantation is the preferred renal replacement therapy for diabetic patients with ESRD and it is associated with a much better survival and quality of life than dialysis among these patients.
Ghaderian et al. (Thu,) conducted a review in Diabetic end-stage renal disease. Kidney transplantation vs. Dialysis was evaluated on Patient survival and quality of life. Kidney transplantation in diabetic patients with end-stage renal disease is associated with better survival and quality of life compared to dialysis.