Physical inactivity (OR 6.48; 95% CI 2.46-9.14), advanced age, male sex, family history, and smoking were significantly associated with progression from elevated blood pressure to hypertension crisis.
Cohort (n=884)
Yes
Advanced age, male sex, family history, smoking, and physical inactivity are significant risk factors for progression to hypertension crisis among patients in Saudi Arabia.
Odds Ratio: 6.48 (95% CI 2.46–9.14)
BACKGROUND: Hypertension is a major global health concern affecting approximately 1.13 billion people worldwide, with most of them residing in developing countries. The aim of this study was to determine the incidence of different stages of hypertension and its associated modifiable and non-modifiable risk factors among patients in military-setting hospitals in Tabuk, Saudi Arabia. METHODS: This retrospective cohort study was conducted at two hospitals in Tabuk, Saudi Arabia. The data were collected from hospital electronic records from 1 January 2019 to 31 December 2019. The blood pressure levels of patients from the last three separate medical visits were recorded. Descriptive statistics and multinomial logistic regression were used for the data analysis. RESULTS: The study included 884 hypertensive patients. The incidences of stage of elevated BP, stage 1, stage 2, and hypertension crisis were 60.0, 29.5, 7.0, and 3.5 cases per 1000 persons. Multivariate analysis indicated that progression from the stage of elevated blood pressure to hypertension crisis was significantly associated with advanced age (odds ratio OR = 3.62, 95% confidence interval CI = 1.99-8.42), male sex (OR = 2.84, 95% CI: 0.57-5.92), and a positive family history of hypertension (OR = 1.95, 95% CI: 1.23-3.09). Other key determinants of the development of stage of elevated blood pressure to hypertension crisis were current smoking status (OR = 1.74, 95% CI: 1.23-4.76), and physical inactivity (OR = 6.48, 95% CI: 2.46-9.14). CONCLUSION: The incidence stage of elevated blood pressure was high among the patients investigated at armed forces hospitals in Tabuk, Saudi Arabia. The logistic regression model proposed in the present study can be used to predict the development of different stages of hypertension. Age, sex, marital status, family history, smoking status, and physical activity play an important role in the development of hypertension. Better strategies to improve awareness, screening, treatment, and management of hypertension are required in Saudi Arabia.
Yagoub et al. (Thu,) conducted a cohort in Hypertension (n=884). Physical inactivity was evaluated on Progression from the stage of elevated blood pressure to hypertension crisis (OR 6.48, 95% CI 2.46-9.14). Physical inactivity (OR 6.48; 95% CI 2.46-9.14), advanced age, male sex, family history, and smoking were significantly associated with progression from elevated blood pressure to hypertension crisis.