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December 27, 2016Advanced Materials118 citationsOpen Access

Light‐Enhancing Plasmonic‐Nanopore Biosensor for Superior Single‐Molecule Detection

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OAOssama AssadTGTal GilboaJSJoshua D. Spitzberg

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Abstract

A stacked plasmonic nanowell–nanopore biosensor strongly suppresses the background fluorescence from the bulk and yields net more than tenfold enhancement of the fluorescence intensity. The device offers extremely high signal-to-background (S/B) ratio for single-molecule detection at ultralow excitation laser intensities, while maintaining extremely high temporal bandwidth for single-DNA sensing. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

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Cite This Study

Assad et al. (2016) studied this question.

synapsesocial.com/papers/6a64106c31344909634808b9https://doi.org/10.1002/adma.201605442
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