Granulomatous Colitis

SINCE the original description of regional ileitis by Crohn, Ginzburg and Oppenheimer1 in 1932 there has been a sustained interest at the Mount Sinai Hospital in granulomatous disease of the bowel. In 1934 Colp2 first described granulomatous disease of both ileum and cecum and demonstrated that the ileocecal valve is no barrier to the development of granulomatous disease in the colon. During the thirty years that have intervened the characteristics and management of granulomatous disease of both small bowel and colon have become progressively better understood.That granulomatous disease can involve the colon alone is clear,3 but the distinctions between . . .