Hospitalized TIA reduces survival compared to the general population, with 91.5% vs 95.0% survival at 1 year and a 20% relative reduction in survival within 9 years.
Cohort (n=22,157)
Does transient ischemic attack reduce long-term survival compared to the general population in adults?
Hospitalization for TIA is associated with a significant long-term reduction in life expectancy, particularly in patients over 65 years of age.
Absolute Event Rate: 91.5% vs 95%
BACKGROUND AND PURPOSE: There is a lack of modern-day data quantifying the effect of transient ischemic attack (TIA) on survival, and recent data do not take into account expected survival. METHODS: Data for 22 157 adults hospitalized with a TIA from July 1, 2000, to June 30, 2007, in New South Wales, Australia, were linked with registered deaths to June 30, 2009. We estimated survival relative to the age- and sex-matched general population up to 9-years after hospitalization for TIA comparing relative risk of excess death between selected subgroups. RESULTS: At 1 year, 91.5% of hospitalized patients with TIA survived compared with 95.0% expected survival in the general population. After 5 years, observed survival was 13.2% lower than expected in relative terms. By 9 years, observed survival was 20% lower than expected. Females had higher relative survival than males (relative risk, 0.79; 95% CI, 0.69-0.90; P65 years.
Gattellari et al. (2011) conducted a cohort in Transient ischemic attack (n=22,157). Transient ischemic attack vs. Age- and sex-matched general population was evaluated on Survival at 1 year. Hospitalized TIA reduces survival compared to the general population, with 91.5% vs 95.0% survival at 1 year and a 20% relative reduction in survival within 9 years.