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July 1, 2009Bioinformatics12 citationsOpen Access

HI: haplotype improver using paired-end short reads

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QLQuan LongDMDaniel G. MacArthurZNZemin Ning

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Abstract

SUMMARY: We present a program to improve haplotype reconstruction by incorporating information from paired-end reads, and demonstrate its utility on simulated data. We find that given a fixed coverage, longer reads (implying fewer of them) are preferable. AVAILABILITY: The executable and user manual can be freely downloaded from ftp://ftp.sanger.ac.uk/pub/zn1/HI.

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Long et al. (2009) studied this question.

synapsesocial.com/papers/6a8591a9916c5a6accadb51bhttps://doi.org/10.1093/bioinformatics/btp412
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