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September 10, 2025Tropical Journal of Natural Product ResearchOpen Access

Hepatoprotective Effect of Ethanol Extract of Chinese Betel Herb (Peperomia pellucida (L.)) On CCl4-Induced Hepatotoxicity in Experimental Animals

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FFFitrya Fitrya

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Overview

Experimental analysis reports decreased liver damage markers in Wistar rats, suggesting benefits of Peperomia pellucida extract.

Key Points

  • The EPP extract significantly reduced liver damage markers like SGPT and SGOT, indicating hepatoprotection.
  • After twenty-one days, EPP treatment groups showed a linear improvement in liver tissue structure based on histopathology.
  • Biochemical parameter analysis confirms the protective effect of EPP against CCl4-induced hepatotoxicity in rats.
  • Normal macroscopic observations of the liver further substantiate the efficacy of EPP as a protective agent.

Cite This Study

Fitrya Fitrya (2025) studied this question.

synapsesocial.com/papers/68c1a41654b1d3bfb60deffdhttps://doi.org/10.26538/tjnpr/v9i7.21
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Also Consider

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  1. 1Immunomodulatory Activity of Chinese Betel (Peperomia pellucida L.) Extract on the Spleen Histopathology in a Murine Model of Gastroenteritis2025
  2. 2Study the hepatoprotective effect of the methanolic extract of Plumbago auriculata Lam. against CCl4-induced hepatocyte damage in mice2024 · 1 citations
  3. 3Hepatoprotective Effect of Ethanolic Extract of Cnestis ferruginea Roots on Carbon tetrachloride-Induced Liver Damage in Male Rats2024
  4. 4Potential Protective Effects of Ethanolic Extract of Butterfly Pea (Clitoria ternatea Linn) Flower Against Carbon Tetrachloride-Induced Hepatotoxicity Rats2024 · 1 citations
  5. 5Toxicological Evaluation of the Ethanol Extract of Peperomia pellucida Leaves in Male Wistar Albino Rats: Hematological, Biochemical, and Histopathological Effects2026