Prospective study reveals improved renal function and hydronephrosis in pediatric patients after pyeloplasty, suggesting effective intervention.
Ureteropelvic junction obstruction (UPJO) is a common cause of paediatric hydronephrosis, often requiring pyeloplasty to preserve renal function. A prospective study (July 2023–December 2024) included 28 children (3 months–12 years) with unilateral UPJO undergoing open dismembered pyeloplasty. Preoperative and postoperative assessments used ultrasonography (Society for Foetal Urology [SFU] grading) and diuretic renography (⁹⁹ TcDTPA) to measure hydronephrosis, glomerular ltration rate (GFR), and differential renal function (DRF). Complications were recorded. Data were analysed using SPSS v27.0 (p<0.05). Of 28 patients (75% male, 71.4% left-sided), 67.9% showed improved renal function and hydronephrosis. Mean SFU grade decreased from 3.07 to 2.14 (30.3%, p<0.001), GFR increased from 30.57 to 32.72 mL/min (7.0%, p=0.049), and DRF improved from 31.76% to 35.61% (12.1%, p<0.001). Complications included urinary tract infection (14.3%), redo pyeloplasty (7.1%), and anastomotic leakage (3.6%). Anderson-Hynes pyeloplasty effectively improves renal function and resolves hydronephrosis in most paediatric UPJO cases, with low complication rates. Early intervention optimizes outcomes
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Verma et al. (2025) studied this question.
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