What question did this study set out to answer?

This work aims to establish the Universal Resonance Model (URM) as a framework for understanding disease progression.

January 10, 2026Open Access

The Universal Resonance Model (URM): A Systems Framework for Dynamic Transitions in Disease

Key Result

The Universal Resonance Model (URM) offers a conceptual framework for understanding disease progression as a dynamic systems process influenced by resilience and metabolic variability.

Key Points

This work aims to establish the Universal Resonance Model (URM) as a framework for understanding disease progression.
Presents a theoretical and conceptual framework of the URM.
Analyzes disease progression through systems thinking.
Situates URM within established theories of complex systems.
URM highlights the loss of resilience in disease progression.
Increased variability in physiological subsystems is key to understanding transitions.
Suggests that interactions among subsystems create resonance.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

This paper presents the Universal Resonance Model (URM), a conceptual framework describing disease progression as a dynamic systems process characterized by loss of resilience, increasing variability, and resonance between interacting physiological subsystems. The article defines the core principles of URM and situates the model within established theories of complex systems, resilience, and early-warning signals. The full theoretical and mathematical development of URM is presented in a companion monograph. This work serves as the primary citable reference for the URM framework. Conceptual framework; no new experimental or clinical data. Suggested citation:Domargård A. The Universal Resonance Model (URM): A Systems Framework for Dynamic Transitions in Disease. Zenodo; 2025. DOI: 10.5281/zenodo.18078350

Mark Helpful

Bookmark

Relay

View Full Paper