Silent Anterior-Segment Remodeling in Fuchs Uveitis Syndrome: Structural and Pupillometric Findings
Abstract
Unilateral FUS exhibits a coherent structural-functional signature: wider angles and deeper ACD, axis-selective anterior steepening, and attenuated photopic constriction with a larger photopic pupil. Combining Scheimpflug anterior-segment metrics with standardized pupillometry provides practical, adjunctive markers that may strengthen diagnostic confidence and sharpen hypotheses on FUS pathophysiology.
Key Points
Objective
To investigate structural and pupillometric changes in unilateral Fuchs Uveitis Syndrome.
Methods
- Analyzed anterior-segment metrics using Scheimpflug imaging.
- Conducted standardized pupillometry assessments.
- Compared angle width, anterior chamber depth, and pupil responses between affected and unaffected eyes.
Results
- Identified wider angles and deeper anterior chamber depths in affected eyes.
- Observed anterior steepening specific to the eye axis.
- Detected attenuated photopic constriction with larger pupils in affected eyes.