Key result
Lp(a) lipoprotein in the upper quartile (≥20.1 mg/dL) increased the odds of myocardial infarction by 2.5 times in men under 60 compared to lower quartiles.
Why the study?
Does elevated Lp(a) lipoprotein increase the risk of myocardial infarction in Hawaiian men of Japanese ancestry?
Population
Hawaiian men of Japanese ancestry (303 with prior myocardial infarction and 408 population-based controls)
Comparison
High Lp lipoprotein levels vs Lower Lp lipoprotein levels
Design
Case-control
Authors
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Lp(a) testing may aid risk stratification in younger Japanese men; extends Lp(a)-MI link beyond white cohorts but remains hypothesis-generating.
Does elevated Lp(a) lipoprotein increase the risk of myocardial infarction in Hawaiian men of Japanese ancestry?
Elevated Lp(a) is an independent risk factor for myocardial infarction in men of Japanese ancestry, demonstrating that its associated cardiovascular risk extends beyond white populations.
George G. Rhoads (1986) studied this question. Lp(a) lipoprotein in the upper quartile (≥20.1 mg/dL) increased the odds of myocardial infarction by 2.5 times in men under 60 compared to lower quartiles.
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