Rare irAes associated with immune checkpoint inhibitor therapy

Key Points

• The aim is to understand the rare immune-related adverse events associated with immune checkpoint inhibitor therapy.
• Review of adverse events across multiple organ systems
• Assessment of diagnostic challenges in attributing causation to immune checkpoint inhibitors
• Discussion on clinical awareness and management strategies
• Rare immune-related adverse events can affect nearly all organ systems.
• Rapid diagnosis and treatment are crucial for managing potential symptoms.
• There's a need for further research on strategies to improve recognition.