• In nutritionally vulnerable adults with calcaneus fractures, closed and percutaneous strategies were associated with higher 2-year subsequent fixation than ORIF. • Percutaneous fixation had lower 90-day wound disruption than ORIF, while overall 90-day infection rates were similar across strategies. • Closed treatment and percutaneous fixation showed higher 90-day acute respiratory failure/mechanical ventilation than ORIF. • These findings underscore the need to individualize fixation strategy in high-risk patients, balancing early soft-tissue morbidity against the likelihood of later conversion to ORIF and reintervention. In nutritionally vulnerable adults with calcaneus fractures, closed and percutaneous strategies were associated with higher 2-year subsequent fixation than ORIF. Percutaneous fixation had lower 90-day wound disruption than ORIF, while overall 90-day infection rates were similar across strategies. Closed treatment and percutaneous fixation showed higher 90-day acute respiratory failure/mechanical ventilation than ORIF. These findings underscore the need to individualize fixation strategy in high-risk patients, balancing early soft-tissue morbidity against the likelihood of later conversion to ORIF and reintervention. Nutritional Vulnerability may increase complications and reintervention after calcaneus fracture care. This study compared 90-day and 2-year outcomes among malnourished adults treated with closed management, percutaneous fixation, or open reduction and internal fixation (ORIF). Adults (≥18 years) with calcaneus fracture and laboratory-defined nutritional vulnerability (albumin ≤3.5 g/dL and/or leukocytes ≤1.5 × 10³/µL within 1 year pre-index) were identified. Three independent 1:1 propensity score-matched comparisons were performed (closed vs ORIF, percutaneous vs ORIF, and closed vs percutaneous). Outcomes were assessed at 90 and 730 days. Matched cohorts included 981 per group (closed vs ORIF), 403 per group (percutaneous vs ORIF), and 386 per group (closed vs percutaneous). At 90 days, closed treatment had higher acute respiratory failure/mechanical ventilation than ORIF (11.5% vs 7.7%, P=.005); otherwise no differences were detected. Percutaneous fixation had lower wound disruption than ORIF (6.2% vs 10.4%, P=.03) but higher acute respiratory failure/mechanical ventilation (13.4% vs 8.2%, P=.017); no differences were detected between closed and percutaneous. By 2 years, subsequent fixation was higher after closed reduction compared to ORIF (6.9% vs 3.8%, P=.002) and percutaneous vs ORIF (9.5% vs 4.0%, P=.002), and salvage procedures were lower after closed reduction compared to ORIF (2.9% vs 4.6%, P=.035); otherwise no differences were detected. Among malnourished adults with calcaneus fracture, less invasive strategies were associated with lower short-term wound disruption compared with ORIF but higher subsequent fixation by 2 years, highlighting clinically important management tradeoffs. These findings underscore the importance of preoperative host optimization and individualized strategy selection in high-risk patients, weighing early soft-tissue morbidity against the potential need for later conversion to ORIF and downstream reintervention in routine practice. Level III, retrospective cohort study.
Saad et al. (Sun,) studied this question.