Cardiac magnetic resonance imaging detected cardiac involvement in 47% of newly diagnosed idiopathic inflammatory myopathies patients compared to 0% in healthy controls (p=0.016).
Observational (n=34)
No
Is cardiac involvement detected by CMR associated with skeletal muscle involvement in newly diagnosed patients with idiopathic inflammatory myopathies?
Cardiac involvement is present in nearly half of newly diagnosed IIM patients and is strongly associated with the severity of skeletal muscle involvement, highlighting the potential utility of early CMR screening in patients with severe myositis.
Effect estimate: p=0.016
Absolute Event Rate: 47% vs 0%
p-value: p=0.016
Cardiac involvement as detected by cardiac magnetic resonance imaging is common at time of diagnosis in patients with IIM and is closely linked to the severity of skeletal muscle involvement.
Hanna et al. (Tue,) conducted a observational in idiopathic inflammatory myopathies (IIM) (n=34). Cardiac magnetic resonance imaging (CMR) assessment with laboratory and clinical evaluation vs. Healthy age- and gender-matched controls (n=9) was evaluated on Presence of cardiac involvement detected by cardiac magnetic resonance imaging based on Updated Lake Louise Criteria (p=0.016, p=0.016). Cardiac magnetic resonance imaging detected cardiac involvement in 47% of newly diagnosed idiopathic inflammatory myopathies patients compared to 0% in healthy controls (p=0.016).