Analysis reveals copy number alterations linked to reduced survival in patients with IDH-mutant astrocytoma, suggesting pathways for targeted therapies.
Patients with hemizygous loss of CDKN2A/B, loss of PTEN, increased number of copy number alterations, specific chromosomal arm losses or rs55705857 germline risk allele have reduced overall survival.
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Drucker et al. (2026) studied this question.
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