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Individuals with post-COVID-19 condition experience more tachycardia during periods of minimal physical activity compared to periods of moderate-to-vigorous physical activity. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

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March 3, 2026Open Access

Associations between heart rate and physical activity in people with post-COVID-19 condition accounting for myalgic encephalomyelitis/chronic fatigue syndrome symptoms

Key Points

Increased tachycardia was observed during minimal physical activity periods, indicating cardiovascular strain.
Participants reported significant increases in heart rate during low activity levels compared to moderate-to-vigorous periods.

Structured PICO

Is minimal physical activity associated with more tachycardia compared to moderate-to-vigorous physical activity in individuals with post-COVID-19 condition?

Population

Individuals with post-COVID-19 condition (PCC) accounting for myalgic encephalomyelitis/chronic fatigue syndrome symptoms

Intervention

Minimal physical activity

Comparator

Moderate-to-vigorous physical activity (MVPA)

Outcome

Tachycardiasurrogate

In patients with post-COVID-19 condition, tachycardia occurs more frequently during minimal physical activity than during moderate-to-vigorous physical activity.

Abstract

Individuals with PCC in our study experienced more tachycardia during periods of minimal physical activity compared with periods categorized as MVPA.

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