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Real-World Outcomes of Heavily Pretreated Relapsed Refractory Multiple Myeloma Patients Treated with Bispecific Antibodies | Synapse
March 3, 2026
Real-World Outcomes of Heavily Pretreated Relapsed Refractory Multiple Myeloma Patients Treated with Bispecific Antibodies
DP
Debolina Pramanik
YC
Yanwen Chen
DB
Diana Basali
Cleveland Clinic
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Key Points
Treatment outcomes in multiple myeloma show significant improvement with bispecific antibodies, especially among heavily pretreated patients.
Overall response rates reached 75% in this population receiving bispecific antibody therapy.
This analysis highlights efficacy through patient records from various healthcare settings with a focus on real-world data.
Using bispecific antibodies demonstrates a promising avenue for therapy in challenging multiple myeloma cases requiring new approaches.
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Pramanik et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76073c6e9836116a2d35a
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.629