Acute and long-term effects of repetitive transcranial magnetic stimulation in major depressive episodes: a systematic review and dose-response meta-analysis of randomized sham-controlled trials

Key Points

• Major depressive episodes improved significantly with repetitive transcranial magnetic stimulation.
• The meta-analysis revealed meaningful outcomes across randomized controlled trials.
• Findings came from a systematic review focusing on dose-response relationships.
• Long-term effects indicate the potential for sustained benefits beyond initial treatment.