Green synthesis of a bacitracin@Ag-CeO 2 nanocomposite@hydrogel for dual antibiofilm and anti-inflammatory therapy against MRSA wound infections

Key Points

• The aim is to develop a novel nanocomposite hydrogel for effective treatment of MRSA wound infections by addressing both biofilm formation and inflammation.
• Utilized green synthesis to create a bacitracin@Ag-CeO2 nanocomposite hydrogel.
• Tested the efficacy of the nanocomposite against MRSA biofilms in vitro.
• Evaluated anti-inflammatory properties in wound healing contexts.
• The nanocomposite showed significant reduction in MRSA biofilm formation.
• Demonstrated anti-inflammatory effects, promoting enhanced wound healing.
• Results suggest improved therapeutic potential over conventional treatments.