基于“脾胃—肠络—肠屏障”一体化病机模型探讨炎症性肠病的“脾虚肠癖”论

Key Points

• This research aims to build an integrated pathogenesis model for inflammatory bowel disease based on historical theories.
• Analyzed classic texts on spleen and stomach theories.
• Reviewed modern research on gut mucosal barriers and microbiota.
• Developed a model linking spleen deficiency with intestinal issues.
• Proposed a model integrating spleen, intestine, and mucosal barriers.
• Highlighted the roles of damp-heat stagnation and microbiome-inflammation imbalance.
• Explained the recurring nature and mixed pathology of inflammatory bowel disease.

Abstract