Does daily aspirin reduce all-cause mortality in apparently healthy older adults?
Daily aspirin in healthy older adults unexpectedly increased all-cause mortality, primarily driven by cancer-related death.
Higher all-cause mortality was observed among apparently healthy older adults who received daily aspirin than among those who received placebo and was attributed primarily to cancer-related death. In the context of previous studies, this result was unexpected and should be interpreted with caution. (Funded by the National Institute on Aging and others; ASPREE ClinicalTrials.gov number, NCT01038583 .).
McNeil et al. (Sun,) studied this question.