What question did this study set out to answer?

The research aims to develop a 3D-printed gyroid scaffold for effective craniomaxillofacial bone regeneration.

March 26, 2026Biomedical MaterialsOpen Access

Biomimetic 3D-printed gyroid scaffolds with versatile bioactive coatings for complex craniomaxillofacial bone regeneration

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Demonstrates enhanced bone regeneration in craniomaxillofacial areas, suggesting new solutions for complex repairs.

The research aims to develop a 3D-printed gyroid scaffold for effective craniomaxillofacial bone regeneration.
Fabrication of scaffolds using poly(L-lactide-co-D,L-lactide) and β-tricalcium phosphate.
Incorporation of a water-soluble support material for controlled porosity.
Mechanical testing to assess compressive strength and elastic modulus.
Chemical and cytotoxicity analyses for biocompatibility.
Biofunctionalization using polydopamine and nanohydroxyapatite.
Scaffolds exhibited optimized compressive strength and elastic modulus.
Confirmed biocompatibility during all stages of processing.
Polydopamine suppressed cell mineralization, while PDA-nHAP enhanced osteogenic differentiation.
Demonstrated suitability for point-of-care fabrication.

Tourbier et al. (2026) studied this question.

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