What does this research mean for the field?

The cumulative incidence of SARS-CoV-2 positivity and severe COVID-19 disease is lower than expected among persons affected by HIV. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To assess SARS-CoV-2 testing practices and positivity among individuals affected by HIV.

March 26, 2026AIDS and BehaviorOpen Access

Low SARS-CoV-2 Positivity in a Large, Diverse US-Based Study of Persons Affected by HIV

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To assess SARS-CoV-2 testing practices and positivity among individuals affected by HIV.
Developed and administered a Health Status Survey from April 2020 to November 2021.
Enrolled children, youth, and adults affected by perinatally and non-perinatally-acquired HIV.
Collected data on SARS-CoV-2 testing uptake, results, and respiratory illness.
Among participants, 43% of PHIV, 35% of NPHIV, and 16% of PHEU reported SARS-CoV-2 testing.
Of those tested, positivity rates were 18% among PHIV, 16% among NPHIV, and 11% among PHEU.
Overall hospitalization for any illness was 4%, while 8% reported respiratory illness worse than a common cold.

Discussion

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Implication

Reports low SARS-CoV-2 positivity in persons affected by HIV, suggesting effective health practices.

Cite This Study

Siminski et al. (2026) studied this question.

synapsesocial.com/papers/69c4cd3efdc3bde448919418 https://doi.org/10.1007/s10461-026-05088-4

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Low SARS-CoV-2 Positivity in a Large, Diverse US-Based Study of Persons Affected by HIV

Key Points

Discussion

Implication

Cite This Study

Low SARS-CoV-2 Positivity in a Large, Diverse US-Based Study of Persons Affected by HIV

Key Points

Discussion

Implication

Cite This Study

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