The Nose–Lung Axis in Chronic Obstructive Pulmonary Disease: An Emerging Interface for Clinical Endotyping, Biomarker Discovery, and Integrated Management

Key Points

• The research aims to explore the interactions between nasal pathology and lung function in COPD.
• Analysis of airflow limitation through spirometry.
• Evaluation of symptom burden and exacerbation history.
• Examination of the nose-lung interface.
• Identifies the nose-lung axis as a significant factor in COPD management.
• Suggests potential biomarkers for clinical use.
• Highlights the need for integrated treatment strategies.