Deferred non-infarct-related arteries with high-risk physiology (QFR <0.88 and QFR-PPG <0.78) had a significantly higher 3-year target vessel failure rate compared to those without high-risk physiology (42.1% vs. 9.9%, HR 5.83).
Observational (n=205)
No
Does QFR-derived physiology stratify high-risk non-infarct-related arteries and guide treatment in patients with acute myocardial infarction?
QFR and QFR-PPG can help stratify risk in intermediate non-infarct-related arteries for patients presenting with acute myocardial infarction.
Effect estimate: HR 5.83 (95% CI 2.87-11.87)
Absolute Event Rate: 42.1% vs 9.9%
p-value: p=<0.001
QFR-derived physiology, including QFR and QFR-PPG, can stratify high-risk non-IRAs and guide optimal treatment in patients with AMI.
Nakao et al. (Wed,) conducted a observational in Acute Myocardial Infarction (AMI) with intermediate non-infarct-related artery stenosis (n=205). High-risk physiology (QFR <0.88 and QFR-PPG <0.78) vs. Without high-risk physiology (QFR ≥0.88 or QFR-PPG ≥0.78) was evaluated on 3-year target vessel failure (TVF) (HR 5.83, 95% CI 2.87-11.87, p=<0.001). Deferred non-infarct-related arteries with high-risk physiology (QFR <0.88 and QFR-PPG <0.78) had a significantly higher 3-year target vessel failure rate compared to those without high-risk physiology (42.1% vs. 9.9%, HR 5.83).