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This study revealed the existence of ferroptosis in the pathophysiology of LTx-CI/R injury. Using Lip-1 to inhibit ferroptosis during CI could ameliorate LTx-CI/R injury, suggesting that Lip-1 administration might be proposed as a new strategy for organ preservation.
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Jin Zhao
Second Affiliated Hospital of Zhejiang University
Jiawei Li
Shanxi Medical University
Wei Dong
Kunming University of Science and Technology
Transplantation
Nanjing Medical University
Second Affiliated Hospital of Zhejiang University
Wuxi People's Hospital
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Zhao et al. (Fri,) studied this question.
synapsesocial.com/papers/69dbd2915b363cdf1c836002 — DOI: https://doi.org/10.1097/tp.0000000000004638