Background Schistosomiasis, a parasitic waterborne infection, remains a major public health challenge in disadvantaged regions, with schoolchildren (5–14 years) at high risk due to frequent water exposure. The study is aimed at assessing the knowledge, attitudes, and practices (KAP) related to schistosomiasis among school‐aged children in Nelson Mandela Bay (NMB) and examining how sociodemographic and environmental factors influence KAP outcomes. Methods A quantitative, descriptive, cross‐sectional study was conducted among 759 schoolchildren aged 5–14 years, enrolled in Grades 0–7. Data were collected using a structured, closed‐ended, interview‐administered questionnaire, which included sections on sociodemographic characteristics, clinical history, and KAP related to schistosomiasis. Bivariate and multivariate analyses were performed to evaluate associations and describe the data using R software (Version 4.3.1). Results Only 11% participants were aware of schistosomiasis, mainly learning from school (62%) or home (35%). Key environmental factors included urinating in rivers (44%), living near water bodies (21.1%), and swimming (11.3%). Knowledge and attitude scores showed a moderate positive correlation ( r = 0.33; p < 0.001). Gender and grade level significantly influenced KAP scores, with males and older children (Grades 4–7) exhibiting better knowledge ( p = 0.015), attitudes ( p = 0.023), and practices ( p = 0.001). Females had lower knowledge scores ( β = −0.15; p = 0.018), while older children displayed fewer positive attitudes ( β = 0.07; p = 0.038) and poorer practices ( β = 0.11; p = 0.001). Conclusion Significant gaps in knowledge, poor attitudes, and inadequate hygiene practices highlight the need for targeted education and community‐based strategies to improve KAP and reduce schistosomiasis risk in NMB schoolchildren.
Vere et al. (Thu,) studied this question.