Objectives/Goals: The Wake Forest Clinical and Translational Science Institute (WF CTSI) provides many services, but little is known about how utilization of services affects research outcomes. Our goal is to understand long-term outcomes of recurrent service use from existing resources with an eye towards creating new processes to track research outcomes. Methods/Study Population: The Dissemination, Implementation, and Continuous Quality Improvement team partnered with the Biostatistics, Epidemiology, and Research Design (BERD) program for this project. Initially, we aimed to track abstract and paper publications, and grant submissions (unfunded and funded) for all service requests coming through the BERD from 2017-2024. This was quickly deemed infeasible using prior CTSI data collection processes; however, detailed follow-up data did exist on funded CTSI pilots in the same time window. Consequently, we aimed to test associations between project attributes provided on the service request form and downstream research outcomes, including peer-reviewed publications and grant funding. We used chi-squared tests in the Python package “tableone” to test these associations. Results/Anticipated Results: Our sample only included WF CTSI pilot-funded projects; though, unexpectedly we found information on pilot projects funded by different sources including center/institutional pilots, federal funding, foundation grants, and internal/departmental funding. We found it most effective to link service requests with IRB numbers, because different principle investigators can submit requests on behalf of the same project. N=206 total projects were included in the analysis. Regarding peer-reviewed publications, associations were found with type of service, principal investigator rank, and IRB approval status. Regarding grant funding, associations were found with service type, principal investigator career stage, and previous principal investigator grant funding. Discussion/Significance of Impact: As part of a large academic learning health system, the WF CTSI provides support to various investigators and tracking long-term research outcomes is a priority. This investigation identified important predictors of successful publications and grants in pilot projects, though it also identified gaps in processes to track research outcomes.
Peluso et al. (Wed,) studied this question.