A high healthy lifestyle index consisting of 6-7 healthy factors reduced the risk of all-cause mortality by 50% (HR 0.50) compared to a low index of 0-2 factors.
Cohort (n=11,395)
Does high adherence to a multidimensional healthy lifestyle index reduce all-cause and cardiovascular mortality in a Chinese community-based cohort?
Adherence to a multidimensional healthy lifestyle, particularly one characterized by non-smoking and low-level alcohol consumption, significantly reduces the risk of all-cause mortality in a Chinese population.
Effect estimate: HR 0.50 (95% CI 0.25-0.99)
Background: Limited evidence was available on the association of the integrated effect of multidimensional lifestyle factors with mortality among Chinese populations. This cohort study was to examine the effect of combined lifestyle factors on the risk of mortality by highlighting the number of healthy lifestyles and their overall effects. Methods: A total of 11,395 participants from the Guangzhou Heart Study (GZHS) were followed up until 1 January 2020. Individual causes of death were obtained from the platform of the National Death Registry of China. The healthy lifestyle index (HLI) was established from seven dimensions of lifestyle, and lifestyle patterns were extracted from eight dimensions of lifestyle using principal component analysis (PCA). Hazard ratios (HRs) and 95% confidence intervals (95% CIs) were estimated using the Cox proportional hazard regression model. Results: = 0.023) when comparing the high with low tertiles of pattern score, after adjustment for confounders. Every 1-unit increment of pattern II score was associated with a decreased risk (HR: 0.97, 95% CI: 0.95-0.99) of all-cause mortality. The other two patterns were not associated with all-cause mortality, and the association of cardiovascular mortality risk was observed with neither HLI nor any lifestyle pattern. Conclusion: The results suggest that the more dimensions of the healthy lifestyle the lower the risk of death, and adherence to the lifestyle pattern characterized with heavier loading of non-smoking and low-level alcohol drinking reduces the risk of all-cause mortality. The findings highlight the need to consider multi-dimensional lifestyles rather than one when developing health promotion strategies.
Hu et al. (Tue,) conducted a cohort in General population (n=11,395). High healthy lifestyle index (6-7 healthy lifestyle factors) vs. Low healthy lifestyle index (0-2 healthy lifestyle factors) was evaluated on All-cause mortality (HR 0.50, 95% CI 0.25-0.99). A high healthy lifestyle index consisting of 6-7 healthy factors reduced the risk of all-cause mortality by 50% (HR 0.50) compared to a low index of 0-2 factors.