Physical activity alters metabolic pathways, including fuel metabolism and mitochondrial oxidation, which may mitigate cardiovascular aging and improve cardiovascular health.
Metabolomics provides a valuable investigative tool to understand the biochemical mechanisms by which physical activity mitigates cardiovascular aging.
The purpose of this review is to explore how metabolomics can help uncover mechanisms through which physical activity may influence the progression of cardiovascular aging. Cardiovascular aging is a process of functional and structural changes in older adults which can progress to cardiovascular disease. Metabolomics profiling is an investigative tool that can track the diverse changes which occur in human biochemistry with physical activity and aging. This mini review will summarize published investigations in metabolomics and physical activity, with a specific focus on the metabolic pathways that connect physical activity with cardiovascular aging.
Lim et al. (Mon,) conducted a review in Cardiovascular aging. Physical activity was evaluated. Physical activity alters metabolic pathways, including fuel metabolism and mitochondrial oxidation, which may mitigate cardiovascular aging and improve cardiovascular health.