Key result
Drug therapy for mild hypertension with diastolic BP <100 mm Hg has not proved beneficial for low-risk patients, who should instead use nondrug therapies for 6 to 12 months.
Why the study?
Does early and aggressive drug therapy improve outcomes compared to nondrug therapies in low-risk patients with mild hypertension?
Population
Patients with mild hypertension, particularly those at low risk for premature cardiovascular disease.
Comparison
Nondrug therapies for at least 6 to 12 months… vs Early and aggressive drug therapy.
Design
Review
Authors
Loading...
Supports initial nondrug approach in low-risk mild hypertension; leaves open need for updated RCTs with contemporary agents.
Does early and aggressive drug therapy improve outcomes compared to nondrug therapies in low-risk patients with mild hypertension?
For low-risk patients with mild hypertension (diastolic BP < 100 mm Hg), a 6- to 12-month trial of non-pharmacologic therapy is recommended over early aggressive drug therapy due to a lack of proven benefit and potential medication risks.
Norman M. Kaplan (1983) conducted a review in Mild hypertension. Drug therapy vs. Nondrug therapies was evaluated. Drug therapy for mild hypertension with diastolic BP <100 mm Hg has not proved beneficial for low-risk patients, who should instead use nondrug therapies for 6 to 12 months.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: