Bioguided phytochemical evaluation of the antiproliferative activity of the ethanolic extract of Skytanthus acutus , an extremophile plant from northern Chile

Key Points

• The aim is to evaluate the antiproliferative activity of the ethanolic extract of Skytanthus acutus against cancer cells.
• Used ethanolic extract of Skytanthus acutus for evaluation.
• Tested antiproliferative effects on HeLa cells at concentrations of 14-84 µM.
• Assessed cytostatic and apoptotic effects.
• The extract displayed antiproliferative activity at 14-84 µM.
• Induced cytostatic effects and apoptosis in HeLa cells.