Overweight and obesity in elderly Chinese residents were significantly correlated with increased asymptomatic target organ damage, including LVMI (p<0.001) and pulse wave velocity (p<0.001).
Cross-Sectional (n=2,098)
Does overweight or obesity correlate with asymptomatic target organ damage in elderly Chinese community-dwelling residents?
Overweight and obesity are significantly associated with asymptomatic target organ damage, including left ventricular hypertrophy, diastolic dysfunction, and arterial stiffness, in elderly Chinese individuals.
p-value: p=<0.05
OBJECTIVE: To investigate the relationship between asymptomatic target organ damage (TOD) and different somatotypes in a population of elderly from Chinese community-dwelling. METHODS: A total of 2098 Chinese senior residents from northern Shanghai older than 65 years were recruited in the research. The following somatotype parameters were recorded and analyzed: body mass index, waist circumference, hip circumference, and waist-hip ratio were recorded and calculated. Asymptomatic TOD, including urine albumin/creatinine ratio, estimated glomerular filtration rate (eGFR), intima-media thickness (IMT), left ventricular mass index (LVMI), left ventricular diastolic function, and carotid-femoral pulse wave velocity (PWV) was recorded using the MyLab30 Gold CV system and SphygmoCor. RESULTS: Of all 2098 residents, 817 (38.9%) were overweight and 289 (13.8%) were obese. All somatotype measures were significantly correlated with TOD parameters (p<0.05). After adjustment for age and male gender, in total population, LVMI (p<0.001), cardiac diastolic function (E/Ea, p<0.001), PWV (p<0.001), eGFR (p=0.03), and urine albumin/creatinine ratio (p<0.001) changed gradually and significantly correlated with increasing BMI values. Obesity and overweight were independently related to the incidence of LVH, LVDD, artery stiffness, carotid arterial plaque, and microalbuminuria. CONCLUSION: The incidence of asymptomatic TOD was significantly correlated with overweight and obesity, especially in women, whereas the underweight may favor in the prevention of TOD.
Xiong et al. (Sat,) conducted a cross-sectional in Asymptomatic target organ damage (n=2,098). Somatotype (overweight and obesity) was evaluated on Asymptomatic target organ damage (including urine albumin/creatinine ratio, eGFR, IMT, LVMI, left ventricular diastolic function, and PWV) (p=<0.05). Overweight and obesity in elderly Chinese residents were significantly correlated with increased asymptomatic target organ damage, including LVMI (p<0.001) and pulse wave velocity (p<0.001).