Key result
Reduced breath-hold 3-5 MOLLI yields similar gadolinium partition coefficient measurements to standard MOLLI.
Why the study?
Does a reduced breath-hold MOLLI T1 mapping protocol with bolus injection accurately determine the partition coefficient of gadolinium compared to standard MOLLI with continuous infusion in normal subjects?
Does a reduced breath-hold MOLLI T1 mapping protocol with bolus injection accurately determine the partition coefficient of gadolinium compared to standard MOLLI with continuous infusion in normal subjects?
A shortened MOLLI T1 mapping protocol with bolus gadolinium injection can accurately quantify myocardial extracellular volume without requiring long breath-holds or continuous infusions.
No takes yet. Share an insight, caveat, or question.
May enable shorter breath-hold T1 mapping for ECV in normals; extends MOLLI techniques but leaves patient validation open.
Salerno et al. (2012) studied Normal volunteers (n=10). Reduced breath-hold MOLLI T1 mapping (3-5 protocol) with bolus injection vs. Standard 3-3-5 MOLLI protocol and continuous infusion method was evaluated on Partition coefficient (λ) of gadolinium. A reduced breath-hold MOLLI T1 mapping protocol (3-5 MOLLI) combined with the bolus injection method produced similar measurements of the gadolinium partition coefficient compared to standard MOLLI.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: