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September 26, 2015CirculationOpen Access

Estimates of Global and Regional Premature Cardiovascular Mortality in 2025

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Key result

Achieving United Nations risk factor targets would reduce projected global premature cardiovascular deaths in 2025 from 7.8 million to 5.7 million.

Why the study?

Does achieving United Nations risk factor targets reduce premature cardiovascular mortality globally by 2025 compared to current trends?

Population

Global population across 188 countries using mortality, risk factor, and relative risk data from the Global…

Comparison

Achieving United Nations risk factor targets for… vs Current risk factor trends continuing to 2025

Design

Other

Follow-up

Projected to 2025

Authors

GRGregory A. RothGeneral CardiologyGNGrant NguyenUniversity of WashingtonMFMohammad H. ForouzanfarAga Khan University

Discussion

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Implication

May inform global CVD prevention policies; leaves open real-world attainability and regional variations.

Structured PICO

Does achieving United Nations risk factor targets reduce premature cardiovascular mortality globally by 2025 compared to current trends?

P
Population
Global Burden of Disease 2013 data for 188 countries used to project premature cardiovascular mortality to 2025 under different risk factor reduction scenarios.
E
Exposure
Achieving United Nations risk factor targets for hypertension, tobacco smoking, diabetes mellitus, and obesity by 2025
C
Comparator
Current risk factor trends continuing to 2025
O
Outcome
Premature cardiovascular disease (CVD) mortality in 2025hard clinical

Main Result

Effect estimate: 26% risk reduction (men), 23% risk reduction (women)

Achieving UN risk factor targets could significantly reduce global premature CVD mortality, though more aggressive targets may be needed for all regions to reach the 25% reduction goal.

Cite This Study

Roth et al. (2015) studied Premature cardiovascular disease. Achieving United Nations risk factor targets vs. Current risk factor trends was evaluated on Premature CVD deaths in 2025 (26% risk reduction (men), 23% risk reduction (women)). Achieving United Nations risk factor targets would reduce projected global premature cardiovascular deaths in 2025 from 7.8 million to 5.7 million.

synapsesocial.com/papers/6a2170f2df884daff757eecahttps://doi.org/10.1161/circulationaha.115.016021

Topics

Women and heart diseaseHypertension managementCardiovascular prevention
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