Summary Brain and central nervous system cancers are a major cause of cancer-related morbidity and mortality in children. However, evidence on long-term trends and inequalities across Asia remains limited. Using Global Burden of Disease 2023 data, we analyzed the burden among children aged 0–14 years in Asia from 1990 to 2023 and projected trends to 2050. Age-standardized incidence, mortality, and disability-adjusted life year (DALY) rates were lower in 2023 than in 1990, but no significant regional trends were observed. Substantial geographical heterogeneity persisted, with higher burdens in Central and Western Asia. Infants bore the highest burden, and boys had higher incidence and mortality than girls. Inequality analyses indicated persistent concentration of burden in lower-socio-demographic index settings. Projections suggested a continued decline in overall burden to 2050 but with considerable uncertainty. These findings highlight persistent regional and socio-economic disparities and require strengthened early diagnosis, treatment access, and survivorship care in resource-limited settings.
Zhang et al. (Mon,) studied this question.