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March 26, 1970New England Journal of Medicine

Variant Angina Pectoris

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Key result

A 52-year-old woman presented with variant angina pectoris, marked ST-segment elevations, and life-threatening arrhythmias despite normal coronary angiograms, with the cause remaining unexplained.

Population

52-year-old woman with variant angina pectoris and normal coronary angiograms

Design

Case_report

Authors

RWRichard B. WhitingMedscapeMKMichael D. KleinWestchester Medical CenterJVJoseph Vander Veer

Discussion

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Implication

Alerts clinicians to arrhythmia risk in unexplained variant angina with normal angiograms; leaves open the causative mechanism.

Key Points

  • To present a case of variant angina pectoris with normal coronary angiograms and unexplained symptoms.
  • Case report of a 52-year-old woman with variant angina pectoris
  • Monitoring of cardiac events including ST-segment elevations
  • Insertion of a transvenous demand pacemaker due to syncope
  • Normal coronary angiograms were observed despite symptoms
  • Marked ST-segment elevations were noted during anginal episodes
  • Patient experienced significant cardiac complications, including syncope and ventricular tachycardia

Study Design

Type

Case Report (n=1)

Structured PICO

P
Population
A 52-year-old woman with variant angina pectoris and normal coronary angiograms.
E
Exposure
Insertion of a transvenous demand pacemaker

This case report describes a patient with variant angina, normal coronary arteries, and severe arrhythmias including complete heart block requiring pacing.

Cite This Study

Whiting et al. (1970) conducted a case report in Variant angina pectoris (n=1). A 52-year-old woman presented with variant angina pectoris, marked ST-segment elevations, and life-threatening arrhythmias despite normal coronary angiograms, with the cause remaining unexplained.

synapsesocial.com/papers/6a2b0fbc45877362ce93b576https://doi.org/10.1056/nejm197003262821303
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Variant Form of Angina Pectoris1960 · 245 citations
  2. 2Relation of Heart Rate and Systolic Blood Pressure to the Onset of Pain in Angina Pectoris1967 · 570 citations
  3. 3Paradox of Normal Selective Coronary Arteriograms in Patients Considered to Have Unmistakable Coronary Heart Disease1967 · 414 citations
  4. 4Localized Disorders in Myocardial Contraction1967 · 618 citations
  5. 5Diagnostic Accuracy of Selective Coronary Cinearteriography1967 · 112 citations