Black, Hispanic, and Asian/Pacific Islander women with preeclampsia had higher odds of in-hospital mortality compared with White women across all income groups.
Observational (n=2,436,991)
Yes
Do racial and socioeconomic disparities affect in-hospital mortality and cardiovascular outcomes in women hospitalized for preeclampsia?
Significant racial and socioeconomic disparities exist in cardiovascular outcomes and mortality during preeclampsia hospitalizations, with Black women experiencing higher risks even at higher income levels.
Background: Preeclampsia is associated with higher in-hospital cardiovascular events and mortality with known disparities by race/ethnicity, but data on the interaction between income and these outcomes remain limited. Objectives: This study investigated racial and socioeconomic disparities in cardiovascular outcomes of preeclampsia at delivery hospitalizations. Methods: We analyzed National Inpatient Sample data using International Classification of Diseases-9th Revision/-10th Revision codes between 2004 and 2019. We identified a total of 2,436,991 delivery hospitalizations with preeclampsia/eclampsia as a primary diagnosis representing White (43.1%), Black (18.4%), Hispanic (18.7%), and Asian or Pacific Islander (A/PI; 3.3%) women. We stratified the population based on median household income (low income, medium income, and high income). Logistic regression and propensity-matched analysis were used for reporting outcomes adjusted for age, hospital region, and baseline comorbidities. Results: Black Hispanic, and A/PI women with preeclampsia had higher in-hospital mortality compared with White women across all groups of income. Hispanic women had lower odds of peripartum cardiomyopathy (PPCM) compared with White women. A significant interaction effect was observed with race/ethnicity and median household income for in-hospital mortality and PPCM with preeclampsia. Furthermore, high-income Black women had higher odds of PPCM, stroke, acute kidney injury, heart failure, cardiac arrhythmia, and venous thromboembolism compared with low-income White women. Conclusions: Women with preeclampsia experience significant racial/ethnic and socioeconomic disparities in inpatient mortality and cardiovascular outcomes at delivery. Across all income groups, Black, Hispanic, and A/PI women experience higher odds of in-hospital mortality compared with White women. Furthermore, high-income Black women had greater odds of many CV complications compared with low-income White women.
Zahid et al. (Mon,) conducted a observational in Preeclampsia (n=2,436,991). Non-White race/ethnicity and income level vs. White race and low income was evaluated on In-hospital mortality and cardiovascular outcomes. Black, Hispanic, and Asian/Pacific Islander women with preeclampsia had higher odds of in-hospital mortality compared with White women across all income groups.