Key result
Idiopathic giant cell myocarditis is characterized by serpiginous areas of myocardial necrosis with giant cells, and a rapid clinical course suggestive of an infective cause.
Case Report (n=11)
Idiopathic giant cell myocarditis is a distinct clinico-pathological entity characterized by myocardial necrosis with giant cells and a rapid clinical course.
Prompts inclusion in fulminant myocarditis differentials; leaves open etiology and management implications.
Eleven cases of idiopathic giant cell myocarditis are described, The pathological features are unmistakable with serpiginous areas of myocardial necrosis, at the margins of which giant cells can be seen on histological examination. The aetiology of the condition remains obscure but associated pathology suggests that altered immunity may be a factor. The rapid clinical course is, however, highly suggestive of an infective cause though none has been found.
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Davies et al. (1975) conducted a case report in Idiopathic giant cell myocarditis (n=11). Idiopathic giant cell myocarditis was evaluated on Pathological features and clinical course. Idiopathic giant cell myocarditis is characterized by serpiginous areas of myocardial necrosis with giant cells, and a rapid clinical course suggestive of an infective cause.
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