Young adults (≤40 years) with STEMI had a significantly lower in-hospital mortality rate compared to older patients (0.9% vs 6.1%, p=0.010).
Observational (n=2,028)
No
Do clinical features, management, and in-hospital outcomes differ between young (≤40 years) and older (>40 years) patients with STEMI?
Young adults (≤40 years) presenting with STEMI have a distinct risk profile characterized by higher rates of smoking and family history, but experience significantly lower in-hospital mortality compared to older patients.
Absolute Event Rate: 0.9% vs 6.1%
p-value: p=0.010
OBJECTIVES: This study was designed to evaluate the demographic and clinical findings and in-hospital management and outcome in patients with an acute ST-segment elevation myocardial infarction (STEMI). MATERIAL AND METHODS: By review of the Cardiovascular Tehran Heart Center Registry (CVDTHCR), 2028 patients were found to have the acute STEMI. We compared the patients' characteristics in 109 (5.4%) subjects 40-years-old. RESULTS: The young patients had less diabetes, hypertension, dyslipidemia and history of MI or prior revascularization, and were more likely to be male (92.7% vs. 74%), smoker (58.7% vs. 31.7%) and have family history of CVD (50.5% vs. 23.4%). The young patients had higher prevalence of angiographically normal coronary artery (13.7% vs. 0.9%; p<0.001). The young patients were more likely to undergo percutaneous coronary intervention (38.5% vs. 18.6%), whereas coronary artery bypass grafting was more common in the old ones (p<0.001). In-hospital death was markedly different among young and old patients (0.9% and 6.1%, respectively; p<0.01). CONCLUSION: In STEMI population, the risk profile, clinical findings and severity of coronary disease of the young differ substantially from the elderly counterparts. Young patients with STEMI have a favorable outcome compared with that in older patients.
Hosseini et al. (Wed,) conducted a observational in ST-segment elevation myocardial infarction (STEMI) (n=2,028). Age ≤ 40 years vs. Age > 40 years was evaluated on In-hospital mortality (p=0.010). Young adults (≤40 years) with STEMI had a significantly lower in-hospital mortality rate compared to older patients (0.9% vs 6.1%, p=0.010).